Objective To observe the effect of different surgical methods on cervical disc herniation(CDH) and its influence on cervical curvature, adjacent segment degeneration and safety. Methods From June 2019 to June 2022, 60 patients with single-segment CDH were randomly divided into group A and group B with 30 patients in each group. Both groups were treated with anterior cervical discectomy and fusion(ACDF), group A was treated with Zero-P internal fixation, and group B was treated with traditional fusion cage plate internal fixation. The operation efficacy, operation condition, C2～7 cervical curvature, Cobb angle, cervical function(JOA score), pain degree(NRS score) and complication rate of the two groups were compared before and after the operation.Results There was no statistically significant difference in the excellent and good rate of surgical effect between Group A and Group B(96.67% vs. 90.00%,χ2/P=0.268/0.605).The operation time, fluoroscopy times and hospital stay in Group A were less than those in Group B(t/P=3.947/<0.001, 2.744/0.008, 3.310/0.002). The curvature and Cobb angle of C2-7 cervical spine in the two groups were higher than those before operation 3 and 6 months after operation(P<0.001), but="" there="" was="" no="" significant="" difference="" between="" the="" two="" p="">0.05). The JOA score of the two groups at 3 and 6 months after operation was higher than that before operation, and the NRS score was lower than that before operation(P<0.001), but="" there="" was="" no="" statistically="" significant="" difference="" between="" the="" two="" p="">0.05). The incidence of complications in group A was lower than that in group B(6.67% vs. 26.67%,χ2/P=4.320/0.038). Conclusion Zero-P or traditional fusion cage plate internal fixation in ACDF of single-segment CDH patients can achieve good surgical effect, effectively improve the anatomical structure and function of cervical spine, and reduce the degree of pain. Zero-P has obvious advantages in shortening the operation time, promoting the postoperative recovery of patients, and reducing the incidence of complications.

This paper reported one case of unilateral pleural effusion caused by primary Sjögren's syndrome, and reviewed the literatures.

This paper reports the clinical data of a patient with familial Mediterranean fever with PR3-ANCA positive recurrent cerebrovascular disease, and reviewed the literature.

Non-reflow after acute myocardial infarction and reperfusion can lead to complete myocardial necrosis, expansion of myocardial infarction area, damage of cardiac function, left ventricular remodeling and heart failure, which seriously affect the short-term and long-term prognosis of patients, and become a major international problem and research hotspot in the cardiovascular field. Tongxinluo capsule, the representative prescription of collateral disease theory, has increasingly shown its advantages in the treatment of myocardial no-reflow. This article reviews the progress of basic and clinical research on the application of Tongxinluo capsule in the prevention and treatment of this disease in the past 10 years.

Exosomes are vesicles secreted by a variety of cells, which contain a variety of substances, such as lipids, proteins, circular RNA(circRNA), long-chain non-coding RNA(lncRNA) and microRNA(miRNA). However, the expression of multiple exosome-derived cyclic RNA in the plasma of patients with gastric cancer is significantly different from that of normal people, which directly or indirectly affects the metabolism, metastasis and prognosis of tumor. Many studies have shown that exocrine-derived cyclic RNA plays an important role in the development and metastasis of gastric cancer. This article focuses on the role of exocrine-derived cyclic RNA in the diagnosis, metastasis and prognosis of gastric cancer.