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《YiNanBing ZaZhi》2024 Vol.22,No.03
  • Exploring the staged treatment of interstitial lung diseases from a microscopic perspective based on the Xuanfu-Feiluo theory
    Author:Dong Hongyan Gao Ming Geng Limei keyword: Interstitial lung disease; Xuanfu; Feiluo; Staged treatment;
    Interstitial lung disease in Chinese medicine belongs to the category of "lung paralysis" and "lung impotence", and its pathogenesis is complex, and clinical diagnosis and treatment are difficult. Its pathogenesis is complex and clinical diagnosis and treatment are difficult. Xuanfu-lung collaterals are mutually complementary microstructures, which are important parts of lung tissues; Xuanfu-lung collaterals are important to "pass", which play the functions of unobstructed qi, infiltration of fluid and blood, and operation of the divine mechanism. The pathogenesis of interstitial lung diseases, characterized by stagnation of qi, condensation of phlegm and obstruction of blood, is closely related to the abnormalities in the structure and function of the Xuanfu-Lung complex. Based on the theory of Xuanfu-Longluo, the article summarizes the staged treatment of interstitial lung diseases with "Qixuan-Tongluo" as the general principle of treatment, wonderful use of pungent flavors, appropriate use of tonic and tonic, and staged treatment, so as to provide a brand-new perspective for the clinical diagnosis and treatment of interstitial lung diseases.
  • Discussion on the pathogenesis of type 2 diabetes mellitus from the spleen theory guided by the theory of disease complex
    Author:Zhang Shaolan Ma Kun Chang Liping Wei Cong keyword:Type 2 diabetes mellitus; Treatment based on spleen; Luobing theory; Qiluo Theory; Mailuo Theory;
    In the past, the Luobing theory of Chinese medicine has been proposed to treat type 2 diabetes mellitus(xerostomia) from the theory of "spleen" under the guidance of the theory of Chinese medicine, and with the formation of two major branches of research in the discipline of Qiluo Theory and vein and network theory, and the research has been deepened in the prevention and treatment of many major clinical diseases, such as cardiovascular diseases, cerebrovascular diseases and diabetes mellitus, the article starts from the core theory of Qiluo Theory, "bearing control and regulating leveling", and discusses the " Qiluo Theory ". With the formation of two branches of research in the discipline of qiluo theory and pulse theory in recent years, and the deepening of research in the prevention and treatment of various major clinical diseases such as cardiovascular diseases, cerebrovascular diseases and diabetes mellitus, the article discusses the abnormalities of "form and qi transformations-qi, blood, fluid, essence and substance-energy metabolism" from the core theory of Qiluo Theory, which is the basis for the treatment of type 2 diabetes. The article starts from the core theory of qi and collaterals theory, "Cheng, Zhi and Ping", and explores the relationship between "transformation of form and qi-qi, blood, fluid, essence and energy metabolism" and the disease; from the theory of collaterals and veins theory, it explores the relationship between the end of the collaterals of Sun and the microvessels of pancreatic islets as well as its influence on the diabetes mellitus, and thus puts forward the therapeutic principle of "transporting the spleen and the fluid and opening the collaterals and veins and veins of the spleen" for the treatment of Type 2 diabetes. Accordingly, we propose the treatment principle of "transporting spleen and fluids and clearing spleen and collaterals" for type 2 diabetes mellitus, in order to open up new ideas for the research of type 2 diabetes mellitus in Chinese medicine.
  • Exploring the pathogenesis of diabetes mellitus and its complications from LncRNA and the progress of Chinese medicine intervention research
    Author:Zhou Ji Zhou Weixiu Zhu Ranran Wang Zichen Yin Yonghui Wang Haiyan keyword:Diabetes mellitus; Diabetic complications; Long chain non-coding RNA; Traditional Chinese medicine; Mechanism; Research progress;
    Diabetes mellitus is a common chronic metabolic disease in clinic, and long-chain non-coding RNAs(LncRNAs) play an important role in the occurrence and development of diabetes mellitus and its complications, and it is one of the hot mechanisms of the current research. In this article, we review the effects of various LncRNAs on the progression of diabetes mellitus and its complications by mediating pathological processes such as inflammatory response, oxidative stress, autophagy, fibrosis, endoplasmic reticulum stress, cell proliferation and apoptosis, and iron death, etc. We summarize the current progress of research on the improvement of diabetes mellitus and its complications through the modulation of LncRNAs by single-flavored traditional Chinese medicines(TCMs) and proprietary Chinese medicine(pCms) with the aim of providing new targets for the R&D of TCM new drugs and providing ideas for the prevention and treatment of diabetes mellitus and its complications. We hope to provide new targets for the research and development of new Chinese medicines and ideas for the prevention and treatment of diabetes mellitus and its complications.
  • The effect of active ingredients of traditional Chinese medicine and plants on diabetic infertility and the related mechanism research progress
    Author:Han Youxin Yang Dan keyword:Diabetes mellitus; Infertility; Traditional Chinese medicine;
    Diabetes mellitus is a group of systemic metabolic disorders characterized by chronic hyperglycemia due to multiple etiological factors, which are mainly due to defects in insulin secretion and/or utilization. Diabetes mellitus can lead to a variety of complications, affecting the heart, blood vessels, eyes, kidneys and nerves, as well as the reproductive system. Current studies have shown that traditional Chinese medicines and plants can ameliorate diabetes mellitus and related complications, and their mechanism of action is mainly to protect target organs from the high-glucose environment by reducing inflammatory responses, attenuating oxidative stress, improving insulin resistance, and stimulating β-cell secretion. The article reviews the active ingredients and effects of traditional Chinese medicine and plants on diabetes insipidus to provide some references for the research of Chinese medicine for diabetes in China, and to provide new options for future dietary therapies for diabetes.